Executive Management Team

Executive Management

Thomas Heydler Photo

Chief Executive Officer

Thomas Heydler

Thomas P. Heydler joined Definiens in 2004. He brings more than 20 years of entrepreneurial expertise and in-depth knowledge of the global software business to Definiens.

Mr. Heydler was President and CEO at Barcelona Design Inc. based in San Jose, USA. Before joining Barcelona, Mr. Heydler served as President and CEO for InterPro Business Solutions, Inc., USA. He was Vice President and Executive Officer at Documentum Inc., a leading software and solutions provider with specific focus on the pharmaceutical and life sciences industry.

He built and drove Documentum’s European operations and assumed worldwide responsibility for Marketing and Documentum’s Application Business subsequently. Prior to this engagement, he served as Vice President and General Manager Europe for Cadence Design Systems and held senior leadership positions at Siemens AG.

Mr. Heydler holds a Diplom-Ingenieur degree in Electric Engineering and Computer Science from the Technical University in Munich.

Markus Rinecker, MD  Photo

Chief Financial Officer

Markus Rinecker, MD

Dr. Markus Rinecker joined Definiens in 2009. He brings more than 10 years of entrepreneurial and finance experience as well as in-depth clinical expertise to the company.

Prior to joining Definiens, Dr. Rinecker served as Managing Director at one of the leading surgical hospitals in Munich. While managing 350 employees with full P&L responsibility, he established a new department for open heart surgery and streamlined organizational processes to increase the organization’s profitabiligy. For the hospital chain Humaine Kliniken GmbH he evaluated potential acquisition targets and participated in multiple share deal transactions. He was also actively involved in the start-up venture ProHealth AG, which opened Europe’s first full clinical proton radiation center for cancer therapy, in March 2009.

Dr. Rinecker holds a Doctoral Degree in Medicine at the Ludwig-Maximilians-University in Munich as well as a Masters Degree in Business Administration of INSEAD, France and Singapore.

Ralf Huss, MD Photo

Chief Medical Officer

Ralf Huss, MD

Dr. Ralf Huss joined Definiens in 2013 and has more than 20 years of training and experience in histopathology and cancer research.

Prior to joining Definiens, Dr. Huss served as Global Head of Histopathology and Tissue Biomarkers at Roche Diagnostics, where he was involved in identifying new tissue biomarkers to stratify cancer patients as part of a global Personalized Healthcare strategy. Dr. Huss also co-founded the biotech company APCETH. He has training and experience in immunology, transplantation biology and stem cell research, has published more than 100 papers, and has worked with the Nobel Laureates Rolf Zinkernagel and E. Donnell Thomas.

In his role as Chief Medical Officer, Dr. Huss plays a key role in expanding Definiens’ image and data analysis into Tissue Diagnostics and Clinical Digital Pathology.

Dr. Huss holds global academic appointments at the Ludwig-Maximilians-University, Munich and the Wake Forest Institute for Regenerative Medicine, USA. He is also a Professor of Systems Biology at the University College Dublin.

Michael Rasche Photo

Chief Commercial Officer

Michael Rasche

Michael Rasche joined Definiens in 2015 bringing 25 years of experience in the healthcare arena, with particular focus on diagnostics and pharma.

He joined Definiens from AYOXXA Biosystems where he was Corporate Vice President of Global Commercial Operations. Prior to that he was Corporate Vice President of Global Marketing and Business Development for Dako (now Agilent Technologies). During his career he has held leadership positions with Roche and Bayer Diagnostics in Europe, the US, and Latin America across 9 different countries. Michael Rasche is excellent at building and mobilizing high-performing international teams who view it as their mission to deliver business critical projects. In his role as Chief Commercial Officer, Mr. Rasche is responsible for continuing the momentum of Definiens driving sales in the strategic expansion from Research into the Clinical Development and Diagnostics Space.

Scientific Advisory Board

Scientific Advisory Board

Gerd Binnig Photo

Gerd Binnig

Dr. Gerd Binnig founded Definiens with the goal to transform the image analysis industry by enabling more data to be extracted for better decisions. Dr. Binnig, along with his colleague Dr. Heinrich Rohrer, was awarded the Nobel Prize for Physics in 1986.

Manfred Dietel, MD Photo

Manfred Dietel, MD

Dr. Manfred Dietel is Director, Institute of Pathology, Campus Charitè-Mitte. He is also a Member of the Board of Directors of the Association of German University Hospitals and a Member of the Board of Directors of the German Society of Pathology.

James L. Gulley, MD, PhD, F.A.C.P. Photo

James L. Gulley, MD, PhD, F.A.C.P.

Dr. Gulley is Director of the Medical Oncology Service, Chief of the Genitourinary Malignancies Branch and Head of the Immunotherapy Section at NCI. He is an internationally recognized expert in cancer immunotherapy with a strong interest in prostate cancer. He serves as the principal investigator on several international clinical trials, among which for a prostate cancer vaccine and several trials using immune checkpoint inhibitors.

David Harrison, MD Photo

David Harrison, MD

David Harrison is Professor of Pathology, and Director of Research, in the School of Medicine, University of St Andrews, Scotland. He holds honorary positions in Universities of Edinburgh and Florida. He is also Director of Development for Laboratory Medicine for the Edinburgh University Hospitals. He chairs the UK government Committee on Carcinogenicity.

Ronald Herbst, PhD Photo

Ronald Herbst, PhD

Dr. Ronald Herbst is Vice President of Research and Development and Head of Oncology Research for MedImmune.  In this role, Ronald is responsible for the overall oncology research strategy and pre-clinical development of novel drug candidates. Ronald joined MedImmune in February, 2006 as associate director of oncology research.  Prior to MedImmune Ronald was Senior Principal Investigator in the Oncology Department at Schering-Plough Biopharma (formerly DNAX).

Dirk Jäger, MD Photo

Dirk Jäger, MD

Dr. Jäger is the Director Medical Oncology, National Center for Tumor Diseases and University Medical Center Heidelberg.

Walter Kolch, MD, FRSE, MRIA Photo

Walter Kolch, MD, FRSE, MRIA

Walter Kolch is Director of Systems Biology Ireland, which was rated amongst the top 5 Systems Biology Institutes worldwide focussing on human disease in 2014.

Holger Moch, MD  Photo

Holger Moch, MD

Dr. Holger Moch is the Director, Medical Division Pathology and Laboratory Medicine at University Hospital in Zurich, Switzerland. He is also a Full Professor of Pathology at the University of Zurich and Chairman, Institute for Pathology, University Hospital Zurich, Switzerland.


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